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Turkey Sandwich


Give those holiday leftovers new life with this simple, satisfying turkey sandwich. Layers of leftover turkey, creamy mayo, crisp lettuce, tomato, cheddar, and a bit of cranberry sauce are tucked between toasted bread for the perfect sweet and savory bite.

close up of a pile of Turkey Sandwich slices
  • Flavor: Savory turkey, tangy cranberry, and creamy mayo come together for the ultimate leftover lunch.
  • Prep Note: The easiest way to enjoy Thanksgiving leftovers with no cooking at all. Everything’s prepped and ready to layer.
  • Swaps: No leftover turkey? Use pre-sliced deli turkey and your favorite cheese for a quick shortcut.
bread , mayonnaise , cranberry sauce , turkey , tomato , lettuce and cheese with labels to make Turkey Sandwich

What You’ll Need:

  • Bread: My family loves sturdy breads like hearty grain bread, ciabatta, rye, or sourdough. Wrap all the ingredients in crisp romaine lettuce for a lighter option.
  • Turkey: Use sliced deli turkey or leftover sliced turkey breast. Add other deli meats like ham, chicken, or cotto salami for variety, or crispy bacon for some extra flavor.
  • Cheese: Choose your cheese; cheddar will give it an extra bite, while mozzarella and provolone will add a milder flavor to the sandwich.
  • Vegetables: Add crunch with lettuce, tomatoes, or cucumbers. For extra creaminess, try sliced avocado.
  • Condiments: Mix mayo with pesto for a flavorful aioli, add a chipotle aioli for a smoky kick, or use honey mustard for a sweet and tangy twist.
  • Variations: Layer in leftover stuffing or drizzle on some gravy to turn it into a hearty, indulgent meal.
leftover Turkey Sandwich with cranberry sauce

More Turkey Sandwich Ideas

  • Hot Open Face: Top slices of turkey on bread, crumble on some dressing, and smother in gravy, like this hot turkey sandwich.
  • Turkey Reuben Panini: If you have a panini press, pile turkey, Swiss cheese, and sauerkraut on buttered rye bread slices, and cook to a golden, crispy crunch. Grilling in a skillet will work too. Serve this one with Thousand Island dressing on the side.
  • Turkey Salad: Make an easy turkey salad recipe and fill croissants or toasted English muffins!
  • Toast the bread, and pat the lettuce and tomatoes dry before layering to keep the sandwich from getting soggy.
  • Warm leftover turkey slightly for a cozy, melty version.
  • Wrap tightly in parchment paper for lunchboxes or picnics.
  • For meal prep, store ingredients separately for up to 3 days, and assemble just before serving.
hot Turkey Sandwich on a cutting board cut into pieces

Storage and Leftovers

Wrap leftover sandwiches tightly and refrigerate up to 1 day for the best texture. Freezing leftovers is not recommended once assembled, but you can freeze leftover turkey up to 4 months!

Perfect Post Holiday Recipes

Did you enjoy this Turkey Sandwich? Leave us a rating and comment below!

image of Everyday Comfort cookbook by Holly Nilsson of Spend With Pennies plus text

Prep Time 15 minutes

Cook Time 0 minutes

Total Time 15 minutes

  • Lightly toast the bread.

  • Spread mayonnaise on 2 of the slices of toasted bread.

  • Top with cheese, turkey, lettuce, and tomatoes. Season with salt & pepper if desired.

  • Spread remaining slices of bread with cranberry sauce and top sandwich.

  • Cut in half and serve.

Top with lettuce, tomatoes, bacon, pickles, or any of your favorite sandwich toppings!  Sandwiches will keep for 1 day in the refrigerator. 

Calories: 383 | Carbohydrates: 16g | Protein: 11g | Fat: 31g | Saturated Fat: 9g | Cholesterol: 49mg | Sodium: 659mg | Potassium: 77mg | Fiber: 1g | Sugar: 14g | Vitamin A: 284IU | Vitamin C: 1mg | Calcium: 204mg | Iron: 1mg

Nutrition information provided is an estimate and will vary based on cooking methods and brands of ingredients used.

Course Lunch, Sandwich, Turkey
Cuisine American
Turkey Sandwich with cranberry sauce with a title
plate of Turkey Sandwich slices with a title
close up of Turkey Sandwich with writing
plated Turkey Sandwich and close up photo with a title

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